Substance Identity
CAS Number 75-45-6
Chemical Name Methane, chlorodifluoro-
Type of substance Organic
SMILES FC(F)Cl
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT QSAR
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.0002
TOPKAT probability of biodegradation 0
EPI Predicted hydrolysis half-life (days) 8.89E+001
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 2,285.13770180437
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
Robust Study Summary (oxidation)
75456.doc
EPI Predicted Atmospheric Oxidation half-life (days) 1,642

Underlying data regarding Bioaccumulation

Empirical Log Kow 1.08
Log Kow predicted by KowWin 0.89
Log BAF T2MTL predicted by Gobas 0.229447546678611
Log BCF 5% T2LTL predicted by Gobas 0.193714157742345
Log BCF Max predicted by OASIS 1.23355842729645
Log BCF predicted by BCFWIN 0.132

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 27.03778
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 708.37
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 1,800.8158
Toxicity to fish (LC50 in mg/l) as predicted by Aster 478.086875
Toxicity to fish (LC50 in mg/l) as predicted by PNN 27.03778
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 37.6
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 412.297
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 22.185
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 7.08E+002

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Intermediate Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Previous assessment through CEPA Toxic Substances List (Schedule 1)

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment