Substance Identity
CAS Number 56-23-5
Chemical Name Methane, tetrachloro-
Type of substance Organic
SMILES C(Cl)(Cl)(Cl)Cl
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 60
MITI probability of biodegradation 0.0167
TOPKAT probability of biodegradation 0
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 999

Underlying data regarding Bioaccumulation

Empirical Log Kow 2.83
Reference (Log Kow) HANSCH,C & LEO,AJ (1985)
Log Kow predicted by KowWin 2.44
Log BAF T2MTL predicted by Gobas 0.56943097507076
Log BCF 5% T2LTL predicted by Gobas 0.565529341621208
Log BCF Max predicted by OASIS 1.96966058168314
Log BCF predicted by BCFWIN 1.479
Experimental BCF (log) 1.65
Reason for pivotal value Highest Vertebrate BCF
Test species BCF/BAF (Latin) Oncorhynchus mykiss
Test species BCF/BAF (Common) Rainbow trout
Mean water concentration (comment) Uncertain; exposure concentration not reported
Water concentration: Measured/Nominal/Uncertain Not Available
RadioLabel No
Exposure duration (days) 4
Exposure duration (comment) Sufficient exposure duration for 80% steady state; K1/K2
Exposure type Not Available
Mean temperature (deg. Celcius) N/A
Exposure route Water (but fed)
Exposure media Fresh Water
Mean measured lipid content (%) 3
Tissue analysed Muscle
Calculation method K1/K2
Reference (BAF/BCF) Neely, W.B., Branson, D.R., Blau, G.E.. 1974. Partition Coefficients to Measure Bioconcentration Potential of Organic Chemicals in Fish.. Environ.Sci.Technol. 8:1113-1115

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 24.3
Experimental result iT (mg/l) 24.3
Test species iT (Latin) Danio rerio
Test species iT (Common) Zebra danio
Final EndPoint iT LC50
Exposure duration iT (hours) 48
Reference iT Testbericht: Wassergefahrdende Stoffe, Fraunhofer-Institut fur Umweltchemie und Okotoxikologie, Schmallenberg (OECDG Data File)
Robust Study Summary iT
RSS - iT revised CAS 56235.doc
56235-AT-LC50-F-Orzlat.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 18.7
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 43.997
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 43.4898
Toxicity to fish (LC50 in mg/l) as predicted by Aster 17.981459
Toxicity to fish (LC50 in mg/l) as predicted by PNN 36.36695
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 41.5
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 9.269
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 3.021
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 4.40E+001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Greatest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Previous assessment through CEPA Toxic Substances List (Schedule 1)

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
IARC Carcinogenicity - Group 2B
NTP Carcinogenicity - Reasonably anticipated to be a human carcinogen
USEPA 1986 Carcinogenicity - Groups B1 and B2
EC Carcinogenicity - Category 3

Underlying data regarding Complex Hazard Assessment