Substance Identity
CAS Number 95-93-2
Chemical Name Benzene, 1,2,4,5-tetramethyl-
Type of substance Organic
SMILES c(c(cc(c1C)C)C)(c1)C
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P Category
Bioaccumulative (B)? No
Rational for B Category
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) 0 to 1T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air-Soil
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 37.5
MITI probability of biodegradation 0.5299
TOPKAT probability of biodegradation 0
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.5214

Underlying data regarding Bioaccumulation

Empirical Log Kow 4
Log Kow predicted by KowWin 4.18
Log BAF T2MTL predicted by Gobas 2.87644040128891
Log BCF 5% T2LTL predicted by Gobas 2.70536414768875
Log BCF Max predicted by OASIS 3.50101035459812
Log BCF predicted by BCFWIN 2.38

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 2.1
Experimental result iT (mg/l) 2.1
Test species iT (Latin) Cancer magister
Test species iT (Common) Dungeness or edible crab
Final EndPoint iT LC50
Exposure duration iT (hours) 96
Reference iT In: D.A.Wolfe (Ed.) Fate and Effects of Petroleum Hydrocarbons in Marine Ecosystems and Organisms, Pergamon Press, NY :210-220
Robust Study Summary iT
95932-AT-LC50-I-duncra-canmag.doc
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 0.888
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 1.2145
Toxicity to fish (LC50 in mg/l) as predicted by Aster 2.035768
Toxicity to fish (LC50 in mg/l) as predicted by PNN 9.45844
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 7.2
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.054
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 0.147
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 8.88E-001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment