Substance Identity
CAS Number 100-44-7
Chemical Name Benzene, (chloromethyl)-
Type of substance Organic
SMILES c(cccc1)(c1)CCl
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? Yes
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air-Water-Soil
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 71
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.2156
TOPKAT probability of biodegradation 0.994
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 3.68773946360153
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
EPI Predicted Atmospheric Oxidation half-life (days) 4.521

Underlying data regarding Bioaccumulation

Empirical Log Kow 2.3
Log Kow predicted by KowWin 2.79
Log BAF T2MTL predicted by Gobas 1.1329095478423
Log BCF 5% T2LTL predicted by Gobas 1.04621903577332
Log BCF Max predicted by OASIS 2.23102182108193
Log BCF predicted by BCFWIN 1.071

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 1.3
Experimental result iT (mg/l) 1.3
Test species iT (Latin) Daphnia mag
Test species iT (Common) Water flea
Final EndPoint iT EC50
Exposure duration iT (hours) 24
Reference iT Z.Wasser-Abwasser-Forsch. 15(1):1-6 (GER) (ENG ABS) (OECDG Data File)
Robust Study Summary iT
100447_AT_EC50_dapmag.doc
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 0.18
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 1.0417
Toxicity to fish (LC50 in mg/l) as predicted by PNN 2.70025
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 6
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.149
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 1.70E-001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Greatest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
EC Carcinogenicity - Category 2
USEPA 1986 Carcinogenicity - Groups B1 and B2
IARC Carcinogenicity - Group 2A

Underlying data regarding Complex Hazard Assessment