Substance Identity
CAS Number 2062-78-4
Chemical Name 2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
Type of substance Organic
SMILES C(c1ccc(F)cc1)(c2ccc(F)cc2)CCCN(CC3)CCC3N4C(=O)Nc5ccccc45
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? Yes
Persistent (P)? Yes
Rational for P QSAR
Bioaccumulative (B)? Yes
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT QSAR
DSL Quantity range (tonnes/year) Unknown Quantity
Basis for Environment Categorization (PiT, BiT, PBiT) if categorized? PBiT

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 182
MITI probability of biodegradation 0
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.0731

Underlying data regarding Bioaccumulation

Empirical Log Kow 6.3
Log Kow predicted by KowWin 6.23
Log BAF T2MTL predicted by Gobas 6.03146037587664
Log BCF 5% T2LTL predicted by Gobas 4.57455402075921
Log BCF Max predicted by OASIS 4.81982368711217
Log BCF predicted by BCFWIN 4.151

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.1038
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 0.249
Toxicity to fish (LC50 in mg/l) as predicted by PNN 14.11399
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 0.1038
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.128
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 1.28E-003

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment