Substance Identity
CAS Number 57-13-6
Chemical Name Urea
Type of substance Organic
SMILES O=C(N)N
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Robust Study Summary (biodegradation result)
57136.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.6882
TOPKAT probability of biodegradation 1
Robust Study Summary (hydrolysis)
57136.doc
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 5.348

Underlying data regarding Bioaccumulation

Empirical Log Kow -2.11
Log Kow predicted by KowWin -1.56
Log BAF T2MTL predicted by Gobas 0.0000540371955876
Log BCF 5% T2LTL predicted by Gobas 0.0005144646215092
Log BCF Max predicted by OASIS 0.94986172713755
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 5
Experimental result iT (mg/l) 5
Test species iT (Latin) Colisa fasciata
Test species iT (Common) Giant gourami
Final EndPoint iT LC50
Exposure duration iT (hours) 96
Reference iT Acta Hydrochim.Hydrobiol. 11(1):145-149
Robust Study Summary iT
57136-AT-LC50-F-Colfas.doc
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 98,845.211
Toxicity to fish (LC50 in mg/l) as predicted by PNN 73.61817
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 42,184.758
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 894.861
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 3.30E+004

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Greatest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
HC PMRA/USEPA 4A Lists 4A Inert

Underlying data regarding Complex Hazard Assessment