Substance Identity
CAS Number 101-61-1
Chemical Name Benzenamine, 4,4 -methylenebis[N,N-dimethyl-
Type of substance Organic
SMILES N(c(ccc(c1)Cc(ccc(N(C)C)c2)c2)c1)(C)C
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? Yes
Meets Environmental Criteria for Categorization? Yes
Persistent (P)? Yes
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT QSAR
DSL Quantity range (tonnes/year) 0 to 1T
Basis for Environment Categorization (PiT, BiT, PBiT) if categorized? PiT

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water-Soil
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 60
MITI probability of biodegradation 0.0037
TOPKAT probability of biodegradation 0
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.05192

Underlying data regarding Bioaccumulation

Log Kow predicted by KowWin 4.37
Log BAF T2MTL predicted by Gobas 3.32805577221335
Log BCF 5% T2LTL predicted by Gobas 3.07089296270506
Log BCF Max predicted by OASIS 3.68072862844793
Log BCF predicted by BCFWIN 2.665

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.0926
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 0.0926
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 1.116
Toxicity to fish (LC50 in mg/l) as predicted by Aster 2.326075
Toxicity to fish (LC50 in mg/l) as predicted by PNN 25.19312
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 3.8
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.059
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 0.204
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 1.12E+000

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
EC Carcinogenicity - Category 2
NTP Carcinogenicity - Reasonably anticipated to be a human carcinogen
USEPA 1986 Carcinogenicity - Groups B1 and B2

Underlying data regarding Complex Hazard Assessment