Substance Identity
CAS Number 74-88-4
Chemical Name Methane, iodo-
Type of substance Organic
SMILES CI
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? Yes
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT QSAR
DSL Quantity range (tonnes/year) >1T to 1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.1747
TOPKAT probability of biodegradation 0
EPI Predicted hydrolysis half-life (days) 1.69E+006
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 148.533950617284
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
Robust Study Summary (oxidation)
74884.doc
EPI Predicted Atmospheric Oxidation half-life (days) 148.4

Underlying data regarding Bioaccumulation

Empirical Log Kow 1.51
Log Kow predicted by KowWin 1.59
Log BAF T2MTL predicted by Gobas 0.474348269998389
Log BCF 5% T2LTL predicted by Gobas 0.414841090307714
Log BCF Max predicted by OASIS 1.48499647209773
Log BCF predicted by BCFWIN 0.463

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 402.1
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 402.1
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 255.566
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 663.8677
Toxicity to fish (LC50 in mg/l) as predicted by Aster 334.868063
Toxicity to fish (LC50 in mg/l) as predicted by PNN 18.78873
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 160.3
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 98.765
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 11.41
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.56E+002

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
EC Carcinogenicity - Category 3

Underlying data regarding Complex Hazard Assessment