Substance Identity
CAS Number 92-88-6
Chemical Name [1,1 -Biphenyl]-4,4 -diol
Type of substance Organic
SMILES Oc(ccc(c(ccc(O)c1)c1)c2)c2
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT Experiment
DSL Quantity range (tonnes/year) 0 to 1T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water-Soil
Experimental Biodegradation half-life (days) Not Available
Robust Study Summary (biodegradation result)
92886.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.2866
TOPKAT probability of biodegradation 0.658
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.2233

Underlying data regarding Bioaccumulation

Log Kow predicted by KowWin 2.8
Log BAF T2MTL predicted by Gobas 1.61542797298268
Log BCF 5% T2LTL predicted by Gobas 1.51998777685237
Log BCF Max predicted by OASIS 2.2328395084415
Log BCF predicted by BCFWIN 1.453

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.397
Experimental result iT (mg/l) 0.397
Test species iT (Latin) Tetrahyme thermophila
Test species iT (Common) Ciliate Protozoa
Final EndPoint iT EC50
Exposure duration iT (hours) 96
Reference iT FU-Berlin, Inst.f.Biochemie und Molekularbiologie, UFO-Plan, F+E-Vorhaben 106 03 083 (OECDG Data File)
Robust Study Summary iT
RSS - iT revised CAS # 92886.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 4.2
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 8.794
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 39.4032
Toxicity to fish (LC50 in mg/l) as predicted by Aster 16.888984
Toxicity to fish (LC50 in mg/l) as predicted by PNN 5.73301
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 2.5
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 18.114
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.44E-001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment