Substance Identity
CAS Number 125-69-9
Chemical Name Morphinan, 3-methoxy-17-methyl-, hydrobromide, (9.alpha.,13.alpha.,14.alpha.)-
Type of substance Organic
SMILES O(c(ccc(c1C(C(C2N(C3)C)CCC4)(C3)C4)C2)c1)C
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT QSAR
DSL Quantity range (tonnes/year) Unknown Quantity

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water-Soil
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 60
MITI probability of biodegradation 0.0143
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.09758

Underlying data regarding Bioaccumulation

Log Kow predicted by KowWin 2.67
Log BAF T2MTL predicted by Gobas 1.48754449036709
Log BCF 5% T2LTL predicted by Gobas 1.39435686509202
Log BCF Max predicted by OASIS 1.26899419457189
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.388
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 0.388
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 4.1
Toxicity to fish (LC50 in mg/l) as predicted by Aster 4.40409
Toxicity to fish (LC50 in mg/l) as predicted by PNN 7.57261
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.39
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.83E-002

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment