Substance Identity
CAS Number 23214-92-8
Chemical Name 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-à-L-l*y*xo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
Type of substance Organic
SMILES COc4cccc5C(=O)c3c(O)c2CC(O)(CC(OC1CC(N)C(O)C(C)O1)c2c(O)c3C(=O)c45)C(=O)CO
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT QSAR
DSL Quantity range (tonnes/year) 0 to 1T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 60
MITI probability of biodegradation 0.0039
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.07391

Underlying data regarding Bioaccumulation

Empirical Log Kow 1.27
Log Kow predicted by KowWin 1.85
Log BAF T2MTL predicted by Gobas 0.324865165332984
Log BCF 5% T2LTL predicted by Gobas 0.278434575020821
Log BCF Max predicted by OASIS 1.61071733556433
Log BCF predicted by BCFWIN -1.212

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 2.74e-005
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 0.0000274
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 98.77
Toxicity to fish (LC50 in mg/l) as predicted by PNN 44.7239
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 13.515
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 5.57E+000

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
NTP Carcinogenicity - Reasonably anticipated to be a human carcinogen
IARC Carcinogenicity - Group 2A

Underlying data regarding Complex Hazard Assessment