Substance Identity
CAS Number 14698-29-4
Chemical Name 1,3-Dioxolo[4,5-g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-
Type of substance Organic
SMILES C1Oc2cc3N(CC)C=C(C(=O)O)C(=O)c3cc2O1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT QSAR
DSL Quantity range (tonnes/year) 0 to 1T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 37.5
MITI probability of biodegradation 0.4285
TOPKAT probability of biodegradation 1
EPI Predicted Ozone reaction half-life (days) 6.549
EPI Predicted Atmospheric Oxidation half-life (days) 0.08494

Underlying data regarding Bioaccumulation

Empirical Log Kow 0.94
Log Kow predicted by KowWin 1.7
Log BAF T2MTL predicted by Gobas 0.172273897089272
Log BCF 5% T2LTL predicted by Gobas 0.144003048237652
Log BCF Max predicted by OASIS 1.53763303912266
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 560.2903
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 2,662.766
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 560.2903
Toxicity to fish (LC50 in mg/l) as predicted by Aster 570.326688
Toxicity to fish (LC50 in mg/l) as predicted by PNN 1,142.44879
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 254.8
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 640.226
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 3.71E+000

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment