Substance Identity
CAS Number 75-52-5
Chemical Name Methane, nitro-
Type of substance Organic
SMILES N(=O)(=O)C
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? Yes
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1T to 1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air-Water
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.6863
TOPKAT probability of biodegradation 1
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 82.2649572649572
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
Robust Study Summary (oxidation)
75525.doc
EPI Predicted Atmospheric Oxidation half-life (days) 82.28

Underlying data regarding Bioaccumulation

Empirical Log Kow -0.35
Log Kow predicted by KowWin -0.04
Log BAF T2MTL predicted by Gobas 0.0000540371955876
Log BCF 5% T2LTL predicted by Gobas 0.0005144646215092
Log BCF Max predicted by OASIS 1.04963874569299
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 278
Experimental result iT (mg/l) 278
Exposure duration iT (hours) 96
Robust Study Summary iT
75525-AT-LC50-F-Pimpro.doc
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 3,742.991
Toxicity to fish (LC50 in mg/l) as predicted by Aster 6,347.3325
Toxicity to fish (LC50 in mg/l) as predicted by PNN 126.9602
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 398.8
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 1,936.506
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 73.184
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 3.74E+003

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Intermediate Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
IARC Carcinogenicity - Group 2B
NTP Carcinogenicity - Reasonably anticipated to be a human carcinogen

Underlying data regarding Complex Hazard Assessment