Substance Identity
CAS Number 59-67-6
Chemical Name 3-Pyridinecarboxylic acid
Type of substance Organic
SMILES O=C(O)c(cccn1)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT QSAR
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 98
Reference (biodegradation result) PITTER,P.; SIMANOVA,J.; RELATION BETWEEN THE MOLECULAR STRUCTURE AND BIODEGRADABILITY OF ORGANIC COMPOUNDS. VIII. BIODEGRADABILITY OF NITROGEN HETEROCYCLIC COMPOUNDS.; SB. VYS. SK. CHEM.-TECHNOL. PRAZE, (ODDIL) F: TEHCNOL. VODY PROSTREDI.; 22:93-113.; 1978
Robust Study Summary (biodegradation result)
59676.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.808
TOPKAT probability of biodegradation 1
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 16.28

Underlying data regarding Bioaccumulation

Empirical Log Kow 0.36
Log Kow predicted by KowWin 0.69
Log BAF T2MTL predicted by Gobas 0.0340720642616583
Log BCF 5% T2LTL predicted by Gobas 0.0276872201476588
Log BCF Max predicted by OASIS 1.17947532100564
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 593.60157
Robust Study Summary iT
59676-AT-EC50-P-tetpyr.doc
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 15,548.938
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 3,521.9873
Toxicity to fish (LC50 in mg/l) as predicted by Aster 1,228.605125
Toxicity to fish (LC50 in mg/l) as predicted by PNN 593.60157
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 2.9
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 2,287.235
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 440.049
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 1.55E+001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Intermediate Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment