Substance Identity
CAS Number 108-95-2
Chemical Name Phenol
Type of substance Organic
SMILES Oc(cccc1)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 85
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.7105
TOPKAT probability of biodegradation 0.993
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 0.406632868610055
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
EPI Predicted Atmospheric Oxidation half-life (days) 0.3196

Underlying data regarding Bioaccumulation

Empirical Log Kow 1.46
Reference (Log Kow) HANSCH,C & LEO,AJ (1985)
Log Kow predicted by KowWin 1.51
Log BAF T2MTL predicted by Gobas 0.44067444398528
Log BCF 5% T2LTL predicted by Gobas 0.383771091320854
Log BCF Max predicted by OASIS 1.4507718663869
Log BCF predicted by BCFWIN 0.424
Experimental BCF (log) 1.24
Reason for pivotal value Only Vertebrate BCF
Test species BCF/BAF (Latin) Brachydanio rerio
Test species BCF/BAF (Common) Zebrafish
Mean water concentration (ug/l) 2,000
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (comment) Uncertain exposure duration; K1/K2
Exposure type Flow-through
Mean temperature (deg. Celcius) 25
Exposure route Water
Exposure media Fresh Water
Mean measured lipid content (%) 4
Tissue analysed Whole body
Calculation method K1/K2
Reference (BAF/BCF) Butte, W., Willing, A., Zauke, G.-P.. 1987. Bioaccumulation of Phenols in Zebrafish Determined by a Dynamic Flow Through Test. QSAR in Environmental Toxicology II pp.43-53 (K.L.E. Kaiser, Ed)

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 5.5
Experimental result iT (mg/l) 5.5
Test species iT (Latin) Daphnia obtusa
Test species iT (Common) Water flea
Final EndPoint iT EC50
Exposure duration iT (hours) 48
Reference iT Environ.Toxicol.Water Qual. 11(3):255-258
Robust Study Summary iT
108952-AT-LC50-I-penchi.doc
108952-AT-EC50-I-Dapobt-3.doc
108952-AT-IC50-I-dapmag.doc
108952-AT-LC50-I-gampul-2.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 25.7
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 27.701
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 118.5519
Toxicity to fish (LC50 in mg/l) as predicted by Aster 53.076227
Toxicity to fish (LC50 in mg/l) as predicted by PNN 10.19238
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 20.1
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 126.854
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 6.72E+001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Greatest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Previous assessment through previous CEPA assessment

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
EC Genotoxicity - Category 3

Underlying data regarding Complex Hazard Assessment