Substance Identity
CAS Number 121-43-7
Chemical Name Boric acid (H3BO3), trimethyl ester
Type of substance Organometallic
SMILES COB(OC)OC
Moiety of concern H3BO3
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Bioaccumulative (B)? Not Determined
Inherently Toxic to Aquatic Organisms (iT)? No
DSL Quantity range (tonnes/year) >1T to 1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Not Applicable
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.3975
EPI Predicted Ozone reaction half-life (days) 999,999
EPI Predicted Atmospheric Oxidation half-life (days) 4.298

Underlying data regarding Bioaccumulation

Log Kow predicted by KowWin -1.9
Log BAF T2MTL predicted by Gobas 0.00069208545400368
Log BCF 5% T2LTL predicted by Gobas 0.0005144646215092
Log BCF Max predicted by OASIS 0.942771698502942
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 60.46
Comment iT LC50 5th percentile. This is another measure of relative standing that can be used for large data sets. There must be a minimum of 19 data points included in the calculation for the 5th%ile to be considered statistically significant. At least 2 studies whose LC50 falls between the 5th%ile and the lowest acceptable value have been critically reviewed. Robust Study Summaries have been prepared for critically reviewed studies.
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 357,000
Toxicity to fish (LC50 in mg/l) as predicted by PNN 343.96634
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 146,000
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 2,720.672
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 3.57E+005

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment